PRELIMINARY STUDIES ON THE PROTECTIVE EFFECT OF SHEA OIL ON THE GONADS OF MALE NORWEGIAN RATS INTOXICATED WITH UNTREATED REFINERY EFFLUENTS
This study reports the possible ameliorative effect of Shea oil on the testes of Norwegian
rats intoxicated with untreated refinery effluent. 3 groups of 10 animals each were treated
with Effluent only, Effluent with Shea oil and an untreated control daily for 9 weeks. Rats
were euthanised at 3, 6 and 9 weeks interval. After 9 week, rats were left for 21 days post-
exposure to recuperate. Body weight, testicular weight and morphology, heavy metal
concentration in testes and histopathology of testes were estimated across the groups.
There was a significant increase (p>0.05) in body and organ weights of treated rats
compared to control. Gross organ morphology also varied widely between treated and
control but this was not statistically significant. Lead and chromium concentrations in the
testes were high in rats treated with effluent only. Histopathology of gonads also showed
evidence of pathological effects in rats treated with effluent only as compared with control
and ameliorated group. Rats treated and ameliorated with Shea oil showed normal
histological architecture in their organs. The study concluded that Shea oil was effective in
ameliorating the effects of untreated refinery effluent toxicity on the gonads of male rats.